arXiv:2607.19973v1 Announce Type: cross Abstract: AI researchers describe state-of-the-art models as one thing repeated at scale: the Transformer, wired identically for text, pixels, or speech. Neuroscientists describe the cortex as a mosaic - dense Layer 4 in visual cortex for spatial encoding, thick Layers 5/6 in motion cortex for temporal integration - different jobs solved by different structures. This paper argues the gap is a structural error, not a stylistic one, and is measurable. A century of cytoarchitecture, from Brodmann to single-cell Patch-seq, shows distinct cognitive functions are implemented by qualitatively different structures, not by rescaling one template. The convolutional neural network is the field's own proof: local receptive fields and hierarchical depth encoded this prior directly, reaching strong image recognition on far less data than later architectures needed. The paper traces how this lesson was discarded: the "Hardware Lottery" made the Transformer the ...