arXiv:2609.13226v1 Announce Type: new Abstract: Machine learning for neglected tropical diseases is limited by data, not algorithms: public annotated image sets for leprosy (Hansen's disease) number in the hundreds, orders of magnitude below what generative models require. We ask whether a model trained on abundant chronic wound photography transfers to this low-data regime. We build a three-stage pipeline. First, a DeepLabV3-ResNet50 segmentation network (validation Dice 0.876, IoU 0.799) supplies lesion masks for two wound datasets that ship without them. Second, we assemble a mask-conditioned latent diffusion model from Stable Diffusion 1.5 components and train it on 3,280 region-of-interest wound crops, widening the UNet input convolution from 4 to 11 channels to admit three mask feature maps and a blurred low-frequency context latent. Third, we fine-tune this model on 708 leprosy image-mask pairs drawn from 764 images of approximately 150 patients. We evaluate with LPIPS perceptua...
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