arXiv:2609.19180v1 Announce Type: new Abstract: Language models face unique challenges in analyzing interdisciplinary scientific research literature. In biophysics research, faithful answers require grounding observed data in source evidence, interpreting it through a quantitative physics model, and linking it to a biological mechanism. To address this challenge, we introduce BioPhys-Bridge, a novel benchmark dataset for evidence-grounded scientific reasoning over biophysical literature. Each case contains evidence blocks, stable evidence IDs, quantitative values, units, equations, assumptions, mechanisms, and next decisions as grounding targets for question answering (QA) and retrieval-augmented generation (RAG). The initial release contains 500 cases, 1,517 agent-facing tasks, and covers six biological domains and nine physical model families, including three sparse families reserved for future expansion. We enforce strict quality gates for all cases in schema, evidence-integrity, qu...